Key Takeaway:
- Wisconsin confirmed its first five mpox cases of 2026 in the southeastern and northern regions of the state.
- Health officials say the public risk remains low, but cases are rising nationwide, with 535 confirmed infections reported.
- Authorities urge high-risk groups and exposed individuals to consult health care providers about vaccination.
Wisconsin health officials reported the state’s first mpox cases of 2026 on Wednesday after identifying a cluster of five infections in southeastern and northern Wisconsin amid a broader rise in cases nationwide.
Health officials confirm five cases across Wisconsin
The Wisconsin Department of Health Services said five mpox cases had been confirmed as of May 3, marking the first infections detected in the state this year. Officials said cases were identified in the southeastern and northern parts of Wisconsin.
Health authorities said mpox remains uncommon but can cause serious illness. The virus spreads through close physical contact, including intimate and face-to-face interactions, and through contact with contaminated materials used by an infected person.
“We are continuing to monitor the situation closely and work with local health partners to limit further spread,” the department said in a statement on Wednesday.
Symptoms include rash, fever, and swollen lymph nodes
According to DHS, common symptoms include an unexplained rash that develops into skin lesions, fever, swollen lymph nodes, muscle aches, and chills.
Officials urged people experiencing symptoms or possible exposure to contact a health care provider. They also encouraged people considered at higher risk of exposure to discuss vaccination options with medical professionals.
Health officials said vaccination may be recommended for gay and bisexual men, men who have sex with men, people with multiple sexual partners in the last six months, travelers with possible sexual exposure in other regions, and individuals who have had close contact with someone infected with mpox.
Health care workers exposed to possible infection also may be advised to receive the vaccine, according to the department.
Nationwide cases continue to increase
The Wisconsin cluster comes as mpox cases increase across the United States. Federal and state health officials reported 535 confirmed cases nationwide as of May 3.
Despite the increase, Wisconsin health officials said the overall risk to the general public remains low. They stressed that awareness, early diagnosis, and vaccination for high-risk groups remain key tools in preventing wider transmission.
Public health agencies across the country continue to monitor infections and trace close contacts as officials work to contain outbreaks before they spread further.
Mpox gained global attention during outbreaks in recent years, prompting vaccination campaigns and public health advisories in several countries.




